Testis Cord Maintenance in Mouse Embryos: Genes and Signaling1
نویسندگان
چکیده
منابع مشابه
Expression of p63 in the testis of mouse embryos.
Apoptosis of testicular germ cells during fetal development is regulated by both p53-dependent and independent mechanisms. However, its precise mechanisms are largely unknown. A member of p53 gene family, p63, is required for p53-dependent apoptosis and can induce apoptosis in the absence of p53 through the activation of p53-target genes. In this study, we examined the expression pattern of p63...
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Gonadotropins are heterodimers consisting an alpha chain (Cgα) and a beta chain. Interestingly, presence of complicated LH-β transcripts in rat testis was accidently found; testicular LH-β transcripts were confined in seminiferous tubules to spermatids, and the translated products were localized in the elongated spermatids. We hypothesized that mouse testis has potential to produce the tissue s...
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Cancer testis antigens (CTAs), a large family of tumor-associated and immunogenic antigens expressed in human tumors of various histological origins, are highly restricted to the testis and trophoblast. CTAs have been identified as potent targets for tumor-specific immunotherapeutic advances and have immensely lead to the development of different clinical trials of CTA-based vaccine therapy bec...
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Embryonic Stem (ES) cells have the potential to form every cell of the body and thus are of great promise for tissue transplantation. One of the rising techniques that allows studying the differentiation state of ES cells is quantitative RT-PCR (qRT-PCR). When relative quantification by qRT-PCR is applied, accurate normalization is necessary, since differentiated embryonic stem cells and develo...
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background: embryo cryopreservation is the process that water is removed from the cell by cryoprotectant materials, and embryos are stored at temperature below zero. this process may affect the viability and developmental potential of embryos. objective: in this study, the effect of the vitrification cryotop method on the expression level of oct4 and mest developmental genes in mouse blastocyst...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 2016
ISSN: 0006-3363,1529-7268
DOI: 10.1095/biolreprod.115.137117